To mark the 16 Days of Activism to End Gender Based Violence and the International Day for Women Human Rights Defenders, Amnesty Canada draws attention to fierce women doing incredible work in unimaginably challenging circumstances. In this article, Amnesty explores the experiences of three powerful women living in prison or under threat of violence due to their activism. In Egypt, Hanan Badr el-Din, motivated by the disappearance of her husband in 2013, co-founded a group that investigates these injustices. However, she was arrested on false charges and sentenced to 5 years in prison. In Guatemala, Maya-K’iche human rights defender, Lolita Chavez, works to defend Indigenous rights against corporate abuses. After significant threats, she now lives under police protection. In Honduras, activists still live in fear, a year after Berta Cáceres was murdered. Attacks and threats of rape and harm continue to be directed towards their daughters. Amnesty Canada calls for action to protect the rights of these courageous women. Photo credit: CORINH